The phenomenon of drunk driving and the increasing number of traffic accidents caused by drunk driving have made it an important task for traffic police departments in various regions to quickly and accurately analyze the alcohol content in the driver's blood. Blood alcohol content detectiongas chromatographCombined with a headspace sampler, it can facilitate accurate detection.

Headspace sampler andgas chromatographWorking principle and advantages:
As an analytical method, headspace analysis is simple and only takes the gas phase for analysis, greatly reducing the interference of sample matrix on analysis As a sample processing method for GC analysis, headspace is relatively simple Secondly, headspace analysis has different modes that can be adapted to various samples by optimizing operating parameters Thirdly, the sensitivity of headspace analysis can meet regulatory requirements Later, combined with the quantitative analysis capability of GC, headspace GC can perform accurate quantitative analysis.
Automatically heat the sample according to the set value after startup; Needle insertion; Charge pressure balance; Sampling; Fill the sample into the quantitative tube; Six way valve switching injection; Start the workstation to start sampling and recording work
Analysis is to determine the content of these components in the original sample by analyzing the gas composition above the sample matrix Obviously, this is an indirect analysis method, and its basic theoretical basis is that there exists a distribution equilibrium between the gas phase and the condensed phase (liquid phase and solid phase) under certain conditions So, the composition of the gas phase can reflect the composition of the condensed phase We can regard headspace analysis as a gas-phase extraction method, which uses gas as a "solvent" to extract volatile components from samples. Therefore, headspace analysis is an ideal sample purification method Traditional liquid-liquid extraction and SPE involve dissolving the sample in a liquid, inevitably leading to some co extracted substances interfering with the analysis Moreover, the purity of the solvent itself is also an issue, which is particularly important in trace analysis Using gas as a solvent can avoid unnecessary interference, as high-purity gases are easily obtainable and cost-effective, which is also an important reason why headspace GC is widely used
Special chromatograph instrument configuration for detecting alcohol content in blood:
1. GC-2001 gas chromatograph with one hydrogen flame detector
2. One (automatic, fully automatic) headspace sampler (sealing forceps, headspace bottle)
3. One dedicated chromatographic column (packed column or capillary column) for alcohol analysis in blood
4. Nitrogen, hydrogen, air source (fully automatic) gas purity 99.999% 1 set
5. One set of data processing system (computer, printer, chromatography workstation)
Operation method:
Connect the GC-2001 gas chromatograph with a headspace sampler and use it together. Under the following conditions, inject the blood sample extracted on site directly into the sampler. After analysis, an accurate analysis report can be obtained.
Using a hydrogen flame ionization detector FID headspace bottle heating temperature of 70-80 ℃
When using capillary chromatography column headspace, control the temperature of the sample injection valve at 70-80 ℃
Gas chromatograph column box temperature: 120 ℃, sample transfer pipeline control temperature: 80 ℃
Detector temperature: 150 ℃ Injection valve Quantification tube volume: 1ml
Vaporization chamber temperature: 100 ℃ Headspace bottle specification: 5ml or 20ml
Headspacegas chromatographApplication scope:
(1) Forensic Science: Testing of volatile toxins such as alcohols, aldehydes, and ketones in blood and urine
(2) Traffic Safety: Testing of Blood Alcohol Content for Vehicle Drivers Drinking and Drunk Driving
(3) Brewing industry: determination of low boiling point aroma components in beer
(4) Food industry: detection of residual 6 # solvent in extracted oil
(5) Environmental protection: Determination of volatile halogenated hydrocarbons in surface water and tap water such as rivers, lakes, etc
(6) Pharmaceutical industry: detection of residual solvents in drugs
(7) Material control: detection of residual acetaldehyde in beverage bottles
(8) Coatings and paints: detection of organic volatile compounds such as benzene, toluene, and xylene in coatings and paints
(9) Packaging printing: detection of residual organic solvents in flexible packaging bags